Pembalap Repsol Honda tersebut berhasil mendapat kemenangan keenam selama enam demam isu di Circuit of The Americas.
Maverick Vinales pebalap Yamaha Movistar finis kedua dan Andrea Iannone (Suzuki Ecstar) ketiga. Keduanya mendapat podium pertama demam isu ini. Sementara Valentino Rossi ada di urutan keempat.
1. Marc Marquez ESP Repsol Honda (RC213V) 41m 52.002s
2. Maverick Viñales ESP Movistar Yamaha (YZR-M1) 41m 55.562s
3. Andrea Iannone ITA Suzuki Ecstar (GSX-RR) 41m 58.706s
4. Valentino Rossi ITA Movistar Yamaha (YZR-M1) 42m 1.589s
5. Andrea Dovizioso ITA Ducati Team (GP18) 42m 5.572s
6. Johann Zarco FRA Monster Yamaha Tech3 (YZR-M1) 42m 6.233s
7. Dani Pedrosa ESP Repsol Honda (RC213V) 42m 10.203s
8. Tito Rabat ESP Reale Avintia (GP17) 42m 20.539s
9. Jack Miller AUS Pramac Ducati (GP17) 42m 20.673s
10. Aleix Espargaro ESP Factory Aprilia Gresini (RS-GP) 42m 20.877s
11. Jorge Lorenzo ESP Ducati Team (GP18) 42m 23.357s
12. Danilo Petrucci ITA Pramac Ducati (GP18) 42m 26.995s
13. Pol Espargaro ESP Red Bull KTM Factory (RC16) 42m 29.266s
14. Takaaki Nakagami JPN LCR Honda (RC213V)* 42m 31.337s
15 Alvaro Bautista ESP Angel Nieto Team (GP17) 42m 32.889s
16 Bradley Smith GBR Red Bull KTM Factory (RC16) 42m 40.477s
17. Scott Redding GBR Factory Aprilia Gresini (RS-GP) 42m 41.997s
18. Thomas Luthi SWI EG 0,0 Marc VDS (RC213V)* 42m 43.117s
19. Cal Crutchlow GBR LCR Honda (RC213V) 42m 51.057s
20. Xavier Simeon ESP Reale Avintia (GP16)* 42m 51.749s
21. Franco Morbidelli ITA EG 0,0 Marc VDS (RC213V)* 42m 52.515s
Gagal Finish
Alex Rins ESP Suzuki Ecstar (GSX-RR) DNF
Hafizh Syahrin MAL Monster Yamaha Tech3 (YZR-M1)* DNF
Karel Abraham CZE Angel Nieto Team (GP16) DNF
1. Andrea Dovizioso 46 poin
2. Marc Marquez 45 poin
3. Maverick Vinales 41 poin
4. Cal Crutchlow 38 poin
5. Johann Zarco 38 poin
6. Andrea Iannnone 31 poin
7. Valentino Rossi 29 poin
8. Jack Miller 26 poin
9. Tito Rabat 22 poin
10. Danilo Petrucci 21 poin
11. Dani Pedrosa 18 poin
12. Alex Rins 16 poin
13. Hafizh Syahrin 9 poin
14. Pol Espargaro 8 poin
15. Aleix Espargaro 8 poin
16. Jorge Lorenzo 6 poin
17. Franco Morbidelli 6 poin
18. Taaki Nakagami 5 poin
19. Scoot Reeding 4 poin
20. Alvaro Bautista 4 poin
21. Karel Abraham 1 poin
22. Thomas Luthi 0 poin
23. Bradley Smith 0 poin
24. Xavier Simeon 0 poin